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Outlook requesting disk

A friend gets the following message when checking her e-mail in Outlook.

"there is no disk in the drive Please insert disk into device harddisk 1 dr2". then she gets a message... "Microsoft Outlook is not responding"

Any ideas?

Copy profile for backup, reinstall Outlook.

Edit: and scan for virii, if possible.

I don't use Outlook so....can you tell me where the file is and is it call "Profile"?

http://support.microsoft.com/default.as ... -us;330137

might be the answer.