O4 - HKLM\..\Run: [AHQInit] C:\Program Files\Creative\SBLive\Program\AHQInit.exe
You don't really need this unless you like playing with your voice (making it sound different).
O3 - Toolbar: ISTbar - {5F1ABCDB-A875-46c1-8345-B72A4567E486} - C:\PROGRA~1\ISTbar\istbar.dll
kill
O4 - HKLM\..\Run: [AdaptecDirectCD] "C:\Program Files\Roxio\Easy CD Creator 5\DirectCD\DirectCD.exe"
Bloatware, you can kill this without any nasty side-effects.
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
Both of these are completely unnecessary. Matter of fact, you don't even need either of them. Use Media Player Classic instead, as it reads QT and RP formats natively.
O4 - HKCU\..\Run: [Weather] C:\PROGRA~1\AWS\WEATHE~1\Weather.EXE 1
Weatherbug...a program notorious for being spyware infested. Uninstall it pronto.
O4 - HKLM\..\Run: [C.tmp] C:\DOCUME~1\DAVIDJ~1\LOCALS~1\Temp\C.tmp.exe 0 28129
O4 - HKLM\..\Run: [E.tmp] C:\DOCUME~1\DAVIDJ~1\LOCALS~1\Temp\E.tmp.exe 1 28129
O4 - HKLM\..\Run: [C.tmp.exe] C:\DOCUME~1\DAVIDJ~1\LOCALS~1\Temp\C.tmp.exe 1 28129
O4 - HKLM\..\Run: [E.tmp.exe] C:\DOCUME~1\DAVIDJ~1\LOCALS~1\Temp\E.tmp.exe 1 28129
Those four don't look legitimate to me.
O4 - HKLM\..\Run: [Internet Optimizer] "C:\Program Files\Internet Optimizer\optimize.exe"
O4 - HKLM\..\Run: [sais] c:\program files\180solutions\sais.exe
O4 - HKLM\..\Run: [BullsEye Network] C:\Program Files\BullsEye Network\bin\bargains.exe
O4 - HKLM\..\Run: [WebRebates0] "C:\Program Files\Web_Rebates\WebRebates0.exe"
O4 - HKCU\..\Run: [Weather] C:\PROGRA~1\AWS\WEATHE~1\Weather.EXE 1
O4 - Startup: Shortcut to KeyCount.exe.lnk = C:\Documents and Settings\David Julian\Desktop\miscelaneous\tkc-release1-61\KeyCount.exe
Kill these for sure.
O8 - Extra context menu item: Web Rebates - file://C:\Program Files\Web_Rebates\Sy1150\Tp1150\scri1150a.htm
O9 - Extra button: SideFind - {10E42047-DEB9-4535-A118-B3F6EC39B807} - C:\Program Files\SideFind\sidefind.dll -
O9 - Extra button: WeatherBug - {AF6CABAB-61F9-4f12-A198-B7D41EF1CB52} - C:\PROGRA~1\AWS\WEATHE~1\Weather.exe (file missing) (HKCU)
Nuke
O15 - Trusted Zone: *.05p.com
O15 - Trusted Zone: *.awmdabest.com
O15 - Trusted Zone: *.blazefind.com
O15 - Trusted Zone: *.clickspring.net
O15 - Trusted Zone: *.flingstone.com
O15 - Trusted Zone: *.frame.crazywinnings.com
O15 - Trusted Zone: *.mt-download.com
O15 - Trusted Zone: *.my-internet.info
O15 - Trusted Zone: *.scoobidoo.com
O15 - Trusted Zone: *.searchbarcash.com
O15 - Trusted Zone: *.searchmiracle.com
O15 - Trusted Zone: *.slotch.com
O15 - Trusted Zone: *.static.topconverting.com
O15 - Trusted Zone: *.xxxtoolbar.com
O15 - Trusted Zone: *.05p.com (HKLM)
O15 - Trusted Zone: *.awmdabest.com (HKLM)
O15 - Trusted Zone: *.blazefind.com (HKLM)
O15 - Trusted Zone: *.clickspring.net (HKLM)
O15 - Trusted Zone: *.flingstone.com (HKLM)
O15 - Trusted Zone: *.frame.crazywinnings.com (HKLM)
O15 - Trusted Zone: *.mt-download.com (HKLM)
O15 - Trusted Zone: *.my-internet.info (HKLM)
O15 - Trusted Zone: *.scoobidoo.com (HKLM)
O15 - Trusted Zone: *.searchbarcash.com (HKLM)
O15 - Trusted Zone: *.searchmiracle.com (HKLM)
O15 - Trusted Zone: *.slotch.com (HKLM)
O15 - Trusted Zone: *.static.topconverting.com (HKLM)
O15 - Trusted Zone: *.xxxtoolbar.com (HKLM)
O15 - Trusted IP range: 206.161.125.149
O15 - Trusted IP range: 206.161.124.130 (HKLM)
O16 - DPF: {386A771C-E96A-421F-8BA7-32F1B706892F} (Installer Class) - h__p://
www.xxxtoolbar.com/ist/softwares/v4.0/0006_adult.cab
Kill those pronto.
O23 - Service: Creative Service for CDROM Access - Unknown - C:\WINDOWS\System32\CTsvcCDA.EXE (file missing)
Totally unnecessary. You don't have to kill it, but its a waste of memory IMO.
O23 - Service: ZESOFT - Unknown - C:\WINDOWS\zeta.exe
Kill that thing immediately!